Wzrokowe potencjały wywołane u dzieci leczonych wersenianem sodowo-wapniowym z powodu podwyższonego poziomu ołowiu we krwi – badanie prospektywne

Introduction
To find out if blood lead level (Pb-B) changes have influence on visual evoked potentials.

Material and methods
18 children (36 eyes) treated with CaNa2EDTA because of chronic environmental lead poisoning were examined two times: first at age 2 – 15.5 (mean 8) years and second 4 years later. For pattern VEP LKC equipment, UTAS E-2000 program and stimulations of 13’, 26’, 52’, 105' were used. P100 amplitude and latency were calculated.

Results
Pb-B was decreased from 150-486 (mean 262) μg/l to 42-248 (mean 103) μg/l. After 4 years, P100 latency was significantly delayed in children with Pb-B above 100 μg/l at second examination. In children with Pb-B below 100 μg/l no significant differences between two consecutive examinations were observed. There were no significant differences in P100 amplitude.

Conclusions
Delayed P100 latency of PVEP in children is permanent but non-progressive if Pb-B is lower than 100 μg/l.