Klinika Oczna

Pełna treść

2/2026 vol. 128
Opis przypadku

Ethambutol-induced toxic optic neuropathy in patients with tuberculosis: a four-case series

Muhammad Rizqy Abdullah 1, 2
,
Antonia Kartika 2, 3
,
Rusti Hanindya Sari 2, 3
,
Dianita Veulina Ginting 2, 3
,
Prettyla Yollamanda 2, 3

  1. Department of Ophthalmology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

  2. National Eye Center, Cicendo Eye Hospital, Bandung, Indonesia

  3. Department of Ophthalmology, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia

KLINIKA OCZNA 2026, 128, 2: 71-79

DOI: https://doi.org/10.5114/ko.2026.163052
Data publikacji online: 2026/07/14
Plik artykułu
KO-00571_EN.pdf
Confronting perimenopausal women’s knowledge of coronary heart disease with their health behaviours. Controversial role of hormone replacement therapy in the protection of coronary heart disease
  1. World Health Organization. Global tuberculosis report 2022. Geneva: World Health Organization; 2022. Available from: https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2022.
  2. Franunfelder FW, Sadun AA, Wood T. Update on ethambutol optic neuropathy. Expert Opin Drug Saf 2006; 5: 615-618.
  3. Chamberlain PD, Sadaka A, Berry S, Lee AG. Ethambutol optic neuropathy. Curr Opin Ophthalmol 2017; 28: 545-551.
  4. Ezer N, Benedetti A, Darvish-Zargar M, Menzies D. Incidence of ethambutol-related visual impairment during treatment of active tuberculosis. Int J Tubercu Lung Dis 2013; 17: 447-455.
  5. Ambika S, Lakshmi KP, Gopal M, Noronha OV. Visual outcomes of toxic optic neuropathy secondary to ethambutol: a retrospective observational study from India, an endemic country. Indian J Ophthalmol 2022; 70: 3389-3392.
  6. Taffner BM, Mattos FB, da Cunha MC, Saraiva FP. The use of optical coherence tomography for the detection of ocular toxicity by ethambutol. PLoS One 2018; 13: e0204655. DOI: 10.1371/journal.pone.0204655.
  7. Kandel H, Adhikari P, Shrestha GS, et al. Visual function in patients on ethambutol therapy for tuberculosis. J Ocul Pharmacol Ther 2012; 28: 174-178.
  8. Grzybowski A, Zulsdorff M, Wilhelm H, Tonagel F. Toxic optic neuropathies: an updated review. Acta Ophthalmol 2015; 93: 402-410.
  9. Sen S, Mandal S, Banerjee M, et al. Ethambutol-induced optic neuropathy: functional and structural changes in the retina and optic nerve. Semin Ophthalmol 2022; 37: 730-739.
  10. Wang MY, Sadun AA. Drug-related mitochondrial optic neuropathies. J Neuroophthalmol 2013; 33: 172-178.
  11. Kim KL, Park SP. Visual function test for early detection of ethambutol-induced ocular toxicity at subclinical level. Cutan Ocul Toxicol 2016; 35: 228-232.
  12. Ministry of Health Republic of Indonesia. Pedoman Nasional Pelayanan Kedokteran: Tata Laksana Tuberkulosis. Jakarta: Ministry of Health Republic of Indonesia; 2020. Available from: https://tbindonesia.or.id/pustaka_tbc/pedoman-nasional-pelayanan-kedokteran-tatalaksana-tuberkulosis/.
  13. Srithawatpong S, Chaitanuwong P, Yospaiboon Y. Factors affecting visual recovery in patients with ethambutol-induced optic neuropathy. Clin Ophthalmol 2023; 17: 545-554.
  14. Irma J, Kartika A, Rini M, et al. A protective role of coenzyme Q10 in ethambutol-induced retinal ganglion cell toxicity: a randomized controlled trial in mice. Neuro-Ophthalmol 2022; 46: 298-303.
  15. Chen HY, Lai SW, Muo CH, et al. Ethambutol-induced optic neuropathy: a nationwide population-based study from Taiwan. Br J Ophthalmol 2012; 96: 1368-1371.
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