Unilateral massive corneal edema: case report and differential diagnosis

Jan Bombuy Gimenez; Justyna Izdebska; Jacek P. Szaflik; Joanna Przybek-Skrzypecka

doi:10.5114/ko.2025.153438

POLSKI

eISSN: 2719-3209
ISSN: 0023-2157

Klinika Oczna / Acta Ophthalmologica Polonica

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abstract:

Case report

Unilateral massive corneal edema: case report and differential diagnosis

Jan Bombuy Gimenez

¹

,

Justyna Izdebska

^{1, 2}

,

Jacek P. Szaflik

^{1, 2}

,

Joanna Przybek-Skrzypecka

^{1, 2}

Department of Ophthalmology, Medical University of Warsaw, Poland
SPKSO Ophthalmic University Hospital in Warsaw, Poland

KLINIKA OCZNA 2025, 127, 3

DOI: https://doi.org/10.5114/ko.2025.153438

Online publish date: 2025/08/19

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Unilateral corneal edema can present significant diagnostic challenges, especially in the absence of prior ocular trauma. This paper describes a case of a 40-year-old male patient with a foreign body sensation in the right eye, which lasted for several weeks. Initial examination revealed unilateral reduction in visual acuity, and a hazy cornea with increased central corneal thickness. A foreign body was removed, and empirical ofloxacin treatment was administered for suspected bacterial keratitis secondary to trauma. However, the lack of sufficient clinical improvement after the implemented treatment suggested other potential diagnoses.

keywords:

Unilateral massive corneal edema: case report and differential diagnosis

Jan Bombuy Gimenez 1 , Justyna Izdebska 1, 2 , Jacek P. Szaflik 1, 2 , Joanna Przybek-Skrzypecka 1, 2

corneal edema, herpetic keratitis, iridocorneal endothelial syndrome

Jan Bombuy Gimenez

¹

,

Justyna Izdebska

^{1, 2}

,

Jacek P. Szaflik

^{1, 2}

,

Joanna Przybek-Skrzypecka

^{1, 2}