Abstract
The influence of dopamine injected into the lateral geniculate body on flash visual evoked response in rats
- Z Katedry i Oddziału Klinicznego Okulistyki w Bytomiu Śląskiej Akademii Medycznej w Katowicach
- Z Katedry i Zakładu Farmakologii w Zabrzu-Rokitnicy Śląskiej Akademii Medycznej w Katowicach
Purpose
Numerous neurotransmitters and neuromodulators operating on all levels of the visual system, influence the parameters of cortical evoked response. The aim of this study was to find the influence of dopamine (DA) injected into the lateral geniculate body (nucleus) on flash visual evoked response (FVEP).
Material and methods
The experiments were performed on adult Wistar rats. They were implanted with 1 caniula conducted into the lateral geniculate body and 2 electrodes: active under the skull on dura mater in occipital region of brain and reference one on the skull in the interorbital region. FVEPs curve before and after injection into the lateral geniculate body 0.9% NaCl and DA were analyzed.
Results
DA in the lateral geniculate body causes increasing latency and amplitude of FVEP peaks.
Conclusions
Dopamine in the lateral geniculate body can improve visual perception in the occipital cortex.
Keywords
visual evoked potentials, lateral geniculate body, dopamine, rats
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