Abstract
1/2007
vol. 109
Original paper
The role of apoptosis in induction ocular changes in patients with cystic fibrosis
- Z Kliniki Okulistyki Dziecięcej Akademii Medycznej w Białymstoku
- Z Zakładu Laboratoryjnej Diagnostyki Pediatrycznej Akademii Medycznej w Białymstoku
- Z III Kliniki Chorób Dzieci Akademii Medycznej w Białymstoku
Klinika Oczna 2007, 109 (1): 22-24
Online publish date: 2007/03/23
Purpose
To evaluate the concentration of sFas in tear film of cystic fibrosis patients
Material and methods
Tear samples were collected from 20 patients with cystic fibrosis and 20 patients from control group. The sFas levels were determined by immunoenzymatic assay ELISA.
Results
We found statistically increased levels of sFas in tear film of patients with cystic fibrosis compared with control group.
Conclusions
Apoptosis may play role in the pathogenesis of ocular changes in cystic fibrosis patients. The above results are important for the choice of the treatment of dry eye syndrome in patients with cystic fibrosis.
Keywords
cystic fibrosis, apoptosis, sFas
Integrated with
