The clinical picture of Horner syndrome and its changes over time in paediatric patients
Department of Ophthalmology, Poznan University of Medical Sciences, Poland
Doctoral School, Poznan University of Medical Sciences, Poland
Department of Paediatric Oncology, Haematology, and Transplantology, Poznan University of Medical Sciences, Poland
KLINIKA OCZNA 2026, 128, 3: 1-5
Introduction
Horner syndrome (HS) typically consists of a triad of symptoms: ipsilateral ptosis, miosis, and anhidrosis. It is caused by an interruption in the oculosympathetic pathway and may be associated with Harlequin syndrome or heterochromia. Literature describes many atypical clinical pictures of this syndrome. We aimed to assess HS clinical image in paediatric patients and its changes over time.
Material and methods
Our study involved data of children with diagnosed HS from our paediatric ophthalmology outpatient clinic. A total of 12 children with HS who presented to our clinic between 2022 and 2024 were included in the study. We performed repeated measurements of pupil diameters as well as palpebral
fissure narrowing measurements, and we analysed the results of the ophthalmological examinations.
Results
We found that in the majority of patients anisocoria became less apparent over time, and in some cases, ptosis also decreased. Heterochromia was present in 25% of children, while 40% of patients reported Harlequin syndrome symptoms.
Conclusions
Our observations indicate that the clinical picture of HS changes over time. In our cohort, ptosis disappeared in some patients with HS over time, and anisocoria became less apparent.
Keywords
Horner syndrome, ptosis, anisocoria, Harlequin syndrome, droopy eyelid
Introduction
Integrated with