Abstract
3/2008
vol. 110
Original paper
The role of chemokines CCL3/ MIP-1 alfa and CCL4/ MIP-1 beta in pathogenesis of dry eye syndrom
- Z Oddziału Chorób Oczu Wojewódzkiego Szpitala Zespolonego w Białymstoku
- Z Kliniki Okulistyki Dziecięcej Dziecięcego Szpitala Klinicznego w Białymstoku
- Z Zakładu Diagnostyki Laboratoryjnej Pediatrycznej Dziecięcego Szpitala Klinicznego w Białymstoku
Online publish date: 2008/09/15
Purpose: To evaluate the concentration of chemokines CCL3/ MIP-1 alfa and CCL4/ MIP-1 beta in film tears in patients with dry
eye syndrom.
Material and methods: Tears samples were collected from 62 patients with dry eye syndrom and 18 patients from control
group. The concentration of chemokines in film tears were determined by immunoenzymatic assay ELISA.
Results: We found statistically increased levels of chemokines CCL3/ MIP-1 alfa and CCL4/ MIP-1 beta in film tears of patients
with dry eye syndrom compared with control group.
Conclusion: Inflammation may play role in pathogenesis of dry eye syndrom.
eye syndrom.
Material and methods: Tears samples were collected from 62 patients with dry eye syndrom and 18 patients from control
group. The concentration of chemokines in film tears were determined by immunoenzymatic assay ELISA.
Results: We found statistically increased levels of chemokines CCL3/ MIP-1 alfa and CCL4/ MIP-1 beta in film tears of patients
with dry eye syndrom compared with control group.
Conclusion: Inflammation may play role in pathogenesis of dry eye syndrom.
Integrated with
