Abstract
4/2012
vol. 114
Review article
Retinal degenerative diseases – mechanisms and perspectives of treatment
- Department of General Ophthalmology, Medical University of Lublin, Lublin, Poland
- Department of Ophthalmology, F. Chopin Specialised Hospital in Rzeszów, Rzeszów, Poland
- Department of Ophthalmology, Pomeranian Medical University, Szczecin, Poland
- Department of Experimental Pharmacology, Polish Academy of Science Medical Research Centre, Warsaw, Poland
Online publish date: 2012/12/12
Retinal degenerative diseases are an extensive group of ocular diseases, leading to vision disorders and finally irreversible vision loss. They are an significant problem, because degenerative processes exist in common ocular disorders like glaucoma or age-related macular degeneration and many other less frequently occurring disorders. In this article, we present mechanisms leading to retinal degeneration like excitotoxicity, oxidative stress, inflammation and summarize the latest reports concerning neuroprotection in the treatment of retina degenerative diseases.
Keywords
retinal degenerative diseases, neuroprotection, excitotoxicity, oxidative stress
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