Abstract
Proton beam radiotherapy of uveal melanoma – preliminary results
- Klinika Okulistyki i Onkologii Okulistycznej Katedry Okulistyki Uniwersytetu Jagiellońskiego Collegium Medicum w Krakowie
- Instytut Fizyki Jądrowej Polskiej Akademii Nauk im. H. Niewodniczańskiego w Krakowie
- Centrum Onkologii, Instytut im. M. Skłodowskiej-Curie, Oddział w Krakowie
Purpose
Presentation of the proton beam radiotherapy (PBR) as a method of treatment of the uveal melanoma patients in the Department of Ophthalmology and Ocular Oncology and Nuclear Physics Institute in Cracow, Poland and their preliminary results.
Material and methods
Nine patients with only choroidal melanoma were treated using PBR between January and April 2011. There were 4 women (44%) and 5 men (56%), a mean age 56 years (38–72). The mean tumor thickness using ultrasounds was 4,14 mm (1,4–9,6 mm).
Results
The mean follow-up was 6 months (5–7). The mean tumor thickness after PBR was 2,47 mm (0–9,3 mm). In 2 patients endoresection of irradiated tumor mass was performed with final flat scar. After exclusion of these patients from analysis, the mean thickness was 3,17 mm (1,5–9,3 mm). In 6 patients the visual function was stable.
Conclusions
The preliminary results show that PBR is highly precise method of uveal melanoma treatment achieving high rates of local control. This method necessitates a close co-operation between ophthalmologist, oncologist, radiotherapists, and medical physicist as well as an elaboration of own procedures of planning and treatment.
Integrated with
