Abstract
Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification
- Department of Ophthalmology, Norbert Barlicki Memorial Teaching Hospital No. 1, Medical University of Lodz, Poland Head: Professor Wojciech Omulecki MD, PhD
- Department of Ophthalmology and Visual Rehabilitation, Central Veterans Hospital, Medical University of Lodz, Poland Head: Professor Piotr Jurowski MD, PhD
Aim
Comparison of efficacy and safety of loteprednol etabonate and bromfenac after phacoemulsification.
Material and methods
Multicenter prospective case series. Consecutive 58 patients (58 eyes) were randomly assigned to the one of the study groups regarding postoperative treatment. Patients in Group I used 0.09% bromfenac 2 times diurnally for 30 days, and patients in Group II used 0.5% loteprednol etabonate 4 times diurnally for 30 days. The laser flare-cell photometry, slit lamp examination, tonometry and optical coherence tomography of macula were performed preoperatively and postoperatively at 1, 7, 30 and 90 days.
Results
The distance best corrected visual acuity was 0. 93 in group I and 0.91 in w group II. Laser Flare Photometry, central macular thickness and intraocular pressure was not significantly different during the 3 months of treatment between the groups (p> 0.05). In both groups, there were no abnormalities in routine slit lamp examination of the anterior and posterior segment.
Conclusions
The results of the study suggest that topical bromfenac and topical loteprednol etabonate had similar effect on laser flare-cell photometry and foveal thickness in the postoperative period after uneventful phacoemulsification.
Keywords
loteprednol etabonate, bromfenac, phacoemulsification, cataract, steroids, NSAID
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