Abstract
Episcleral brachytherapy for intraocular retinoblastoma with 106Ruthenium plaque: analysis of 13 procedures
- Department of Ophthalmology, Children’s Memorial Health Institute in Warsaw, Poland
- Department of Oncology, Children’s Memorial Health Institute in Warsaw, Poland
- Department of Nuclear Medicine, Children’s Memorial Health Institute in Warsaw, Poland
Aim of the study
To evaluate the efficacy of 106Ru episcleral brachytherapy for the treatment of retinoblastoma.
Material and methods
Retrospective series of all 13 children with retinoblastoma treated with 106Ru plaques at the Department of Ophthalmology of the Children’s Memorial Health Institute in Warsaw between 01.01.2015 and 31.12.2020.
Results
A total of 13 tumors were treated with 106Ru brachytherapy. In all cases it was a salvage treatment for tumors resistant to other treatment modalities, after a mean of 3.15 relapses. Overall tumor control was achieved in 12 cases (92.3%). Tumor recurrence was observed in 1 case (7.7%) which led to enucleation. Radiation complications included persistent hemorrhages from neovascularization in 4 cases (30.8%).
Conclusions
106Ru brachytherapy can be an effective salvage treatment for retinoblastoma.
Keywords
episcleral brachytherapy, plaque radiotherapy, retinoblastoma, ruthenium
Integrated with
