Abstract
2/2010
vol. 112
Case report
Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) – a therapeutic dilemma
- Z Katedry Okulistyki Kliniki Okulistyki i Onkologii Okulistycznej Uniwersytetu Jagiellońskiego Collegium Medicum w Krakowie
Online publish date: 2010/07/21
Purpose: To present a rare idiopathic inflammation of the posterior segment of the eye - acute posterior multifocal placoid pigment epitheliopathy (APMPPE).
Material and methods: A 17 years old male patient was referred to the Department of Ophthalmology of Medical College, Jagiellonian University in Krakow with the diagnosis of bilateral choroiditis of unknown etiology. The patient underwent the basic
ophthalmological examination followed by fluorescein (FA) and indocyanine green (ICGA) angiography. Laboratory testing for
Lyme disease, sarcoidosis and syphilis, as well as genetic testing, to determine the presence of HLA antigen complex, were
performed
Results: Based on the outcomes of performed investigations the definitive diagnosis of APMPPE was established. Systemic steroidotherapy was initiated due to rapid progression of the inflammatory changes, progression of the central visual field changes
and profound visual acuity deterioration.
Conclusions: APMPPE is a rare, inflammatory and idiopathic eye disease with no clear indications for pharmacological therapy.
However decision about necessity and sort of pharmacological therapy should be taken under consideration individually for each
patient.
Material and methods: A 17 years old male patient was referred to the Department of Ophthalmology of Medical College, Jagiellonian University in Krakow with the diagnosis of bilateral choroiditis of unknown etiology. The patient underwent the basic
ophthalmological examination followed by fluorescein (FA) and indocyanine green (ICGA) angiography. Laboratory testing for
Lyme disease, sarcoidosis and syphilis, as well as genetic testing, to determine the presence of HLA antigen complex, were
performed
Results: Based on the outcomes of performed investigations the definitive diagnosis of APMPPE was established. Systemic steroidotherapy was initiated due to rapid progression of the inflammatory changes, progression of the central visual field changes
and profound visual acuity deterioration.
Conclusions: APMPPE is a rare, inflammatory and idiopathic eye disease with no clear indications for pharmacological therapy.
However decision about necessity and sort of pharmacological therapy should be taken under consideration individually for each
patient.
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