The influence of the nitric synthase inhibitor 
(L-NAME) on the intraocular pressure 
in endotoxin induced uveitis
in rats

Stanisław Szymaniec; Marta Misiuk-Hojło

eISSN: 2719-3209
ISSN: 0023-2157

Klinika Oczna / Acta Ophthalmologica Polonica

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2/2002
vol. 104

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abstract:

Experimental research

The influence of the nitric synthase inhibitor (L-NAME) on the intraocular pressure in endotoxin induced uveitis in rats

Stanisław Szymaniec

¹

,

Marta Misiuk-Hojło

²

Z Zakładu Terapii Doświadczalnej Instytutu Immunologii i Terapii Doświadczalnej Polskiej Akademii Nauk we Wrocławiu
Z Kliniki i Katedry Okulistyki Akademii Medycznej we Wrocławiu

Online publish date: 2002/06/29

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We studied the influence of the nitric synthase inhibitor (L-NAME) on the induction of uveitis in Wistar rats. The inflammation was induced by a footpad injection of endotoxin in rat. The clinical signs were evaluated in a slit-lamp, the intraocular pressure was measured using Tono Pen tonometer. We showed, that in endotoxin-induced uveitis the intraocular pressure elevation was observed and that L-NAME application reduced the inflammation and the level of the intraocular pressure.

keywords:

The influence of the nitric synthase inhibitor (L-NAME) on the intraocular pressure in endotoxin induced uveitis in rats

Stanisław Szymaniec 1 , Marta Misiuk-Hojło 2

nitric oxide, experimental uveitis

Stanisław Szymaniec

¹

,

Marta Misiuk-Hojło

²