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2/2005
vol. 107 abstract:
Original paper
IFN-γ in tear fluid in patients with cystic fibrosis
Małgorzata Mrugacz
1
,
Beata Żelazowska
2
,
Alina Bakunowicz-Łazarczyk
1
,
Jolanta Wysocka
2
,
Alina Minarowska
3
Klinika Oczna 2005, 107(4-6): 287-288
Online publish date: 2005/07/02
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Introduction
To evaluate IFN-γ concentration in tear fluid in CF patients. Material and methods Tear samples were collected from 15 CF patients at the age 10-21, and from 15 patients in control group at the age 11-20. Cytokine levels were determined by ELISA. Results The concentration of IFN-γ in tear fluid in CF patients was 10.75±2.23 pg/ml, and 4.06±0.57 pg/ml in control group. Conclusions The results of this study indicate that increased concentration of IFN-γ in the tear fluid may be an important factor in the pathogenesis of dry eye in CF patients. They also open new perspectives related to therapeutic management. keywords:
cystic fibrosis, interferon-gamma |
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POLSKI
