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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
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SCImago Journal & Country Rank
4/2019
vol. 121
 
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abstract:
Original paper

Diffuse Diabetic Macular Edema – 18 Months Observation of the 577 nm Subthreshold Micropulse Laser Treatment Results

Małgorzata Latalska
1
,
Agata Prokopiuk
1
,
Jerzy Mackiewicz
1

1.
Department of Vitreoretinal Surgery, Medical University of Lublin Head: Professor Jerzy Mackiewicz, MD, PhD
Online publish date: 2020/03/31
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Purpose
To evaluate the efficacy of subthreshold micropulse laser treatment in diabetic macular edema at 18 months of follow-up.

Material and methods
112 eyes of 112 patients with diabetic macular edema were treated with subthreshold micropulse yellow laser and followed up every 3 months. If the edema was present, the treatment was repeated. The mean age of patients was 65.64±8.75 years. The mean duration of diabetes was 14.4±8.75 years. The glycated hemoglobin level was ≤ 7mg% only in 18 patients. The primary outcomes were the mean change in best-corrected distance and near visual acuity and central macular thickness. Secondary outcomes included variables correlation with glycated hemoglobin level.

Results
The mean baseline best-corrected distance visual acuity was 0.31±0.2 and improved finally to 0.47±0.2 (p=0.00). The mean baseline best-corrected near visual acuity was 1.08±0.8 and improved finally to 0.56±0.2 (p=0.00). The mean baseline central macular thickness was 449.16±162.5 µm and improved finally to 256.6±118.2 µm (p=0.01). The laser treatment was performed in 7 patients one time, in 16 - two times, in 73 - three times, and in 16 - four times. There was no significant correlation between glycated hemoglobin level and disease duration, baseline and final best-corrected distance and near visual acuity and central macular thickness. There was significant negative correlation between glycated hemoglobin level and patients’ age.

Conclusions
Subthreshold micropulse yellow laser showed long-term efficacy in diabetic macular edema treatment. The level of glycated hemoglobin was not important for initial distance and near best-corrected visual acuity and central macular thickness.

keywords:

diabetes mellitus, diabetic macular edema, micropulse laser

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