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2/2006
vol. 108 abstract:
Original paper
Concentration of interleukine-8 in tears in patients with cystic fibrosis
Małgorzata Mrugacz
1
,
Beata Żelazowska
2
,
Alina Bakunowicz-Łazarczyk
1
,
Alina Minarowska
3
,
Jolanta Wysocka
2
Online publish date: 2006/06/25
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Purpose
To evaluate IL-8 concentration in tears fluid in cystic fibrosis patients Material and methods Tears samples were collected from 18 CF Patients and 18 normal controls. Cytokine level was determined by ELISA. Results A significant increase of IL-8 concentration in tears fluid was found in CF patients compared with controls. Conclusions Increase IL-8 concentration in tears fluid in CF patients suggests a role of immunologic processes in the pathogenesis of the ocular changes, and may be a marker of the inflammatory status in ocular surface in cystic fibrosis. keywords:
cystic fibrosis, tears, interleukin-8 |
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POLSKI
